Beilstein J. Org. Chem.2013,9, 2910–2915, doi:10.3762/bjoc.9.327
developed using an efficient fragment coupling protocol which proceeded in good overall yield.
Keywords: azepane; balanol; Garner’s aldehyde; PKCinhibitor; ring-closing metathesis; Introduction
Protein kinase C (PKC) is a family of phospholipid-dependent kinases that phosphorylate serine and threonine